SELECTIVE CELLULAR UPTAKE AND DRUGGABILITY EFFICACY THROUGH FUNCTIONALIZED CHITOSAN-CONJUGATED POLYAMIDOAMINE (PAMAM) DENDRIMERS

Selective Cellular Uptake and Druggability Efficacy through Functionalized Chitosan-Conjugated Polyamidoamine (PAMAM) Dendrimers

Nanotechnology has ushered in significant advancements in drug design, revolutionizing the prevention, diagnosis, and treatment of various diseases.The strategic utilization of nanotechnology to enhance drug loading, delivery, and release has garnered increasing attention, leveraging the enhanced physical and chemical properties offered by these sy

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Metabolic heterogeneity of apolipoprotein B in the rat

Triglyceride-rich lipoprotein apoprotein catabolism was studied in rats from 5 to 60 min after intravenous injection of 125I-labeled lipoproteins.The plasma and liver labeled apoprotein content was analyzed by gel filtration column chromatography using an elution buffer containing 1% sodium dodecyl sulfate.The method resolved two B apoproteins of l

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